Where to Buy Medical Cannabis for Glaucoma: A US Buying Guide
A US guide to buying medical cannabis for glaucoma: licensed dispensaries, delivery, telehealth cards, online retailers, dosing limits, and legal checks.
Short answer
Cannabis can lower intraocular pressure (IOP) for a short time. The effect lasts about 3 to 4 hours per dose. That is too short for practical glaucoma treatment. No study shows cannabis stops optic nerve damage or prevents blindness from glaucoma. Major eye organizations do not recommend it for glaucoma.
What glaucoma is
Glaucoma damages the optic nerve. High IOP is the main risk factor. About 3 million people in the U.S. have glaucoma. Standard care uses prescription eye drops, laser treatment, or surgery to lower IOP around the clock.
medical marijuana for glaucoma reviews
How cannabis lowers IOP
THC, the main psychoactive compound in cannabis, binds to CB1 receptors in the eye. These receptors sit in the ciliary body, which makes aqueous humor, and in the trabecular meshwork, the drain for that fluid. THC cuts fluid production and improves outflow. Smoked or vaporized cannabis lowers IOP by about 25 percent at peak. Peak effect comes 60 to 90 minutes after smoking. The effect is gone in 3 to 4 hours.
medical marijuana for glaucoma reviews
Why it is not a treatment
- Glaucoma needs 24-hour pressure control. Cannabis wears off in 3 to 4 hours.
- A patient would need 6 to 8 doses per day, including during sleep, to keep IOP down.
- Side effects include fast heart rate, low blood pressure, dizziness, impaired coordination, and dependence.
- Smoking adds lung risks.
- No long-term trial shows cannabis protects the optic nerve or saves vision.
- No cannabis-based eye drop exists. Topical THC does not dissolve well enough to work.
CBD is different
CBD does not lower IOP. A 2018 study found a single dose of CBD raised IOP by about 18 percent in healthy adults and in people with glaucoma. CBD may block THC at the CB1 receptor.
medical marijuana for glaucoma reviews
Current status
The FDA has not approved any cannabis product for glaucoma. The American Academy of Ophthalmology and the National Eye Institute state that marijuana is not recommended for glaucoma treatment. Some patients use cannabis for other symptoms. That is separate from IOP control. Ask an eye doctor before changing any glaucoma plan.