Beginner-friendly strains for anxiety have high CBD and low THC, or a balanced 1:1 ratio. THC doses above 10 mg can increase anxiety. Start with 1-2 mg THC. Wait two hours before taking more.

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How THC and CBD affect anxiety

THC binds to CB1 receptors in the brain. At low doses, THC can reduce anxiety. At high doses, THC can cause paranoia, racing thoughts, and a fast heartbeat. CBD does not bind CB1 receptors. CBD changes the receptor shape and lowers anxiety. A 2019 study in The Permanente Journal gave 300 mg CBD to 57 men. The men reported less anxiety. For smoking or vaping, 5-10 mg CBD may help.

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Strain traits to look for

Avoid sativa-dominant strains with THC above 20%. Examples include Sour Diesel and Green Crack.

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Beginner-friendly strains

Harlequin

CBD to THC ratio around 5:2. THC 7-10%. CBD 10-15%. Users report clear-headed relaxation. Low risk of anxiety.

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Cannatonic

THC 6-8%. CBD 6-12%. Balanced ratio. A good first strain for anxiety.

ACDC

THC below 1%. CBD 15-20%. Minimal psychoactive effects. No high. Useful for daytime anxiety.

Northern Lights

Indica. THC 15-18%. Calming and sedating. Start with one small puff. Wait 15 minutes.

Granddaddy Purple

Indica. THC 17-20%. Relaxing. Can cause couch-lock. Use in the evening. Keep dose low.

Dosing and method

  1. Start with 1-2 mg THC.
  2. Wait two hours before taking more.
  3. Use a vaporizer at 180-190 C (356-374 F).
  4. Avoid edibles for the first use. Edibles take 30-120 minutes to work. Effects are stronger.
  5. Keep CBD oil or a high-CBD strain on hand. CBD can reduce THC anxiety.

What to avoid

When to talk to a doctor

Cannabis can trigger panic attacks. A 2020 study in Lancet Psychiatry found a link between cannabis use and increased anxiety. Do not use cannabis if you have a history of psychosis, heart disease, or are pregnant. Talk to a doctor before using cannabis for anxiety.